Call: 1-734-604-2386 Email: [email protected]
Genome Editing Services
Targeted Overexpression with CRISPR
Our targeted overexpression service allows for the precise and controlled expression of your gene of interest at specific genomic loci, including safe harbor sites like AAVS1. Compared with Lentivirus induced overexpression, targeted overexpression can provide more precision regulation and more safety and controllable knock-in effects. This service is ideal for:
- Inducible or constitutive overexpression of target genes
- Ensuring high-level, stable expression in your cell line
- Requiring more accurate regulations, including inducible promoters.
CRISPR Knock-Out
We employ an optimized CRISPR-Cas9 system along with precisely designed guide RNAs (gRNAs) to achieve high knockout efficiency in both adherent and cancer cell lines. Our tailored knockout strategies are customized to meet your specific experimental requirements, ensuring reliable and reproducible results. Our services target a broad range of genomic loci, from exonic regions to safe harbor sites, minimizing off-target effects. We also provide thorough validation of knockout efficiency through genomic and expression analyses, including PCR, sequencing, and Western blotting.
- Available in two formats: lentivirus and standard plasmids
- Custom-designed guide RNAs (gRNAs) for maximum knockout efficiency
- Ideal for functional genomics and pathway analysis
CRISPR RNA Knockdown
We offer CRISPR-based RNA knockdown services that specifically target and degrade RNA transcripts, effectively reducing the expression of your gene of interest at the transcriptional level. Compared to traditional RNA interference (RNAi), CRISPR RNA technologies generally provide more efficient knockdown and greater target specificity.
- Efficient RNA degradation using CRISPR/Cas13 technology
- Ideal for high-throughput screening and gene function analysis
- Offers a more dynamic and precise approach to gene silencing than conventional methods
CRISPR RNA Knockdown
We offer CRISPR-based RNA knockdown services that specifically target and degrade RNA transcripts, effectively reducing the expression of your gene of interest at the transcriptional level. Compared to traditional RNA interference (RNAi), CRISPR RNA technologies generally provide more efficient knockdown and greater target specificity.
- Efficient RNA degradation using CRISPR/Cas13 technology
- Ideal for high-throughput screening and gene function analysis
- Offers a more dynamic and precise approach to gene silencing than conventional methods
Genome Editing Kits
Targeted Overexpression Plasmid Kit
(CDS-P011k) $899 2-3 weeks
Transform your research with our innovative tool to integrate your interest genes into the safe harbor site AAVS1. Our targeted overexpression kit is optimized for use in various cancer cell lines, achieving a remarkable success rate in establishing stable cell lines.
Your Success is Our Commitment!
We guarantee that our kit will successfully generate stable overexpression clones in your transfectable cell lines. If it doesn’t work, you’ll receive a full refund.
For additional services related to stable cell lines, please reach out to us at [email protected].
CRISPR Knock-Out Plasmid Kit
(COT-P031k) $790 2-3 weeks
Our knockout kit offers a fast and efficient solution to disrupt target genes in various cell lines, facilitating the creation of stable cell lines. It includes three all-in-one plasmids featuring optimized Cas9, gRNA structures, and selection markers for improved gene knockout efficiency.
Guaranteed Success!
We guarantee that our kit will successfully generate stable knockout clones in your transfectable cell lines. If it doesn’t work, you’ll receive a full refund.
For additional services related to stable cell lines, please get in touch with us at [email protected].
CRISPR Knock-Out Lentivirus Kit
(COM-P032k) $1,499 2-3 weeks
Our knockout lentivirus kit harnesses advanced lentivirus technology to deliver all-in-one CRISPR knockout functional cassettes, expanding your applications across a broader range of cell lines. The kit includes a single tube of virus with three mixed gRNA sequences, streamlining your experimental process.
Guaranteed Results!
We guarantee that our kit will successfully generate stable knockout clones in your transfectable cell lines. If it doesn’t work, you’ll receive a full refund.
For additional services related to stable cell lines, please contact us at [email protected].
CRISPR RNA Knock-Down Plasmid Kit
(CRT-P051k) $790 2-3 weeks
Our CRISPR RNA knockdown kits offer a highly specific and powerful alternative to traditional RNAi methods for reducing RNA expression levels. Achieve effective inhibition of target gene RNA levels by over 70% across a wide range of applications.
Guaranteed Efficiency!
We stand by our promise: our kit will efficiently inhibit your target genes in transfectable cell lines. If it doesn’t work, you’ll receive a full refund.
For any inquiries, please contact us at [email protected].
Why Choose Us?
- Tailored CRISPR solutions designed to align with your specific research objectives
- Affordable, high-quality services with fast turnaround times
- Comprehensive CRISPR platform compatible with a wide range of cell lines